The Houston Texans (5-5) stay home at NRG Stadium on Thursday, November 20, 2025 to clash with the Buffalo Bills (7-3).

How to watch Buffalo Bills vs. Houston Texans

• Venue: NRG Stadium
• Time: 8:15 p.m. ET
• Streaming (in-market viewers): Fubo (Stream now)
• TV: Amazon Prime Video
• Watching in person? Get tickets on StubHub.

Buffalo vs. Houston odds

• Spread: Buffalo -6 (-110), Houston +6 (-110)
• Favorite Moneyline: Buffalo -285
• Underdog Moneyline: Houston +230
• Total: 43.5
• Total Over Odds: -115
• Total Under Odds: -105

Odds provided by BetMGM.

Injury reports

Bills

DT Phidarian Mathis: questionable (Shoulder)

TE Dalton Kincaid: out (Hamstring)

CB Taron Johnson: Full Participation in Practice (Groin)

DE Joey Bosa: Full Participation in Practice (Wrist)

LB Terrel Bernard: Full Participation in Practice (Ankle)

CB Christian Benford: Full Participation in Practice (Groin)

WR Curtis Samuel: out (Elbow)

S Jordan Poyer: Full Participation in Practice (Nir – Rest)

OG Connor McGovern: Full Participation in Practice (Ankle)

DT DaQuan Jones: Full Participation in Practice (Nir – Rest)

WR Mecole Hardman: out (Calf)

LB Dorian Williams: Full Participation in Practice (Groin)

OLB Shaq Thompson: Full Participation in Practice (Hamstring)

WR Khalil Shakir: Did Not Participate In Practice (Personal)

DT Jordan Phillips: Full Participation in Practice (Wrist)

WR Josh Palmer: Full Participation in Practice (Knee)

Texans

TE Dalton Schultz: Full Participation in Practice (Shoulder)

S Jalen Pitre: out (Concussion)

OT Tytus Howard: Full Participation in Practice (Ankle)

WR Nico Collins: Full Participation in Practice (Ankle)

OT Trent Brown: Full Participation in Practice (Hand)

DE Denico Autry: Full Participation in Practice (Knee)

DE Will Anderson Jr.: Full Participation in Practice (Ankle)

LB Azeez Al-Shaair: Full Participation in Practice (Knee)

QB C.J. Stroud: out (Concussion)

LB Jamal Hill: out (Hamstring)

TE Cade Stover: Full Participation in Practice (Foot)

QB Davis Mills: Full Participation in Practice (Elbow)

OG Ed Ingram: Full Participation in Practice (Knee)

K Ka’imi Fairbairn: Full Participation in Practice (Quad)

CB Myles Bryant: Full Participation in Practice (Ankle)

Stats to know

• The Bills have put an average of 29.2 points per game on the board this season, 12.9 more than the 16.3 the Texans have surrendered.
• Buffalo has a 129.3-yard advantage in average yards gained versus yards allowed compared to Houston (387.4 to 258.1). Buffalo averages 6.4 yards per play, while Houston gives up 4.9.
• The Bills’ defense has allowed 22.9 points per game this year, close to the same as the 22.0 the Texans have scored.
• Buffalo’s defense has given up 322.7 yards per game this season, just 6.9 yards fewer than the 329.6 Houston’s offense has averaged. Houston picks up 5.4 yards per play, while Buffalo allows 5.8.

This watch guide was created using technology provided by Data Skrive.

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