Big Ten opponents match up when the No. 21 Michigan Wolverines (6-2) and the Purdue Boilermakers (2-6) square off on Saturday, November 1, 2025 at Michigan Stadium.
How to watch Purdue Boilermakers vs. Michigan Wolverines
Purdue vs. Michigan odds
Odds provided by BetMGM.
Stats to know
- Michigan has put roughly the same amount of points on the board per game this season (29.0) as Purdue has allowed (27.8).
- Michigan’s offense has averaged 410.9 yards per game this season, within 16.3 yards of the 394.6 Purdue’s defense has allowed.
- This season Purdue puts up 5.5 more points per game (22.9) than Michigan surrenders (17.4).
- Purdue collects 389.1 yards per game, 81.6 more yards than the 307.5 Michigan allows
A third of the Big Ten is on bye this week, but both Michigan and Michigan State are in action a week after their annual clash. Ohio State hosts Penn State in a matchup that looked much juicier in August and Indiana hits the road looking to stay perfect.
MLive’s college football writers will pick them all, against the spread, as they have for every Big Ten game this season. Here are the standings through nine weeks:
Jacob Richman: 49-37
Aaron McMann: 47-39
Andrew Kahn: 39-47
Ryan Zuke: 39-47
Matt Wenzel: 38-48
This week’s games, all of which are on Saturday, are below. Kickoff times are Eastern and odds are courtesy of FanDuel Sportsbook.
Penn State at Ohio State
- When: noon
- TV: FOX | Fubo (free trial) | DirecTV Stream | Sling TV
- Line: Ohio State -20.5
This game was circled in red leading up to the season and throughout Penn State’s nonconference performance. But then the Nittany Lions haven’t won since Sept. 13, and the No. 1 Buckeyes are expected to keep that losing streak going.
MLive staff picks:
- Penn State +20.5: Zuke
- Ohio State -20.5: Kahn, McMann, Richman, Wenzel
Rutgers at Illinois
- When: noon
- TV: NBC | Fubo (free trial) | DirecTV Stream | Sling TV
- Line: Illinois -12.5
Rutgers eked out its first Big Ten win last week against Purdue. Illinois, once considered a Big Ten title dark horse candidate, is on a two-game losing streak.
MLive staff picks:
- Rutgers +12.5: McMann, Wenzel, Zuke
- Illinois -12.5: Kahn, Richman
Indiana at Maryland
- When: 3:30 p.m.
- TV: CBS | Fubo (free trial) | DirecTV Stream | Sling TV
- Line: Indiana -21.5
Under Curt Cignetti, Indiana remains a machine. The Hoosiers are coming off a 50-point win over UCLA. Maryland’s only Big Ten win is over Wisconsin.
MLive staff picks:
- Indiana -21.5: Kahn, McMann, Wenzel
- Maryland +21.5: Richman, Zuke
USC at Nebraska
- When: 7:30 p.m.
- TV: NBC | Fubo (free trial) | DirecTV Stream | Sling TV
- Line: USC -6.5
USC has never lost to Nebraska, owning a 5-0-1 lead in the series, including last year’s win in Los Angeles.
MLive staff picks:
- USC -6.5: Kahn, McMann, Richman, Wenzel, Zuke
Michigan State at Minnesota
- When: 3:30 p.m.
- TV: BTN | Fubo (free trial) | DirecTV Stream | Sling TV
- Line: Minnesota -3.5
The Spartans are seeking their first Big Ten win against a Minnesota team that will need to regroup after a 41-3 loss to Iowa.
MLive staff picks:
- Minnesota -3.5: Kahn, McMann, Richman, Wenzel, Zuke
Purdue at Michigan
- When: 7 p.m.
- TV: BTN | Fubo (free trial) | DirecTV Stream | Sling TV
- Line: Michigan -20.5
The Wolverines will try to avoid a letdown after a rivalry win and keep their Big Ten title and playoff hopes alive. Purdue hasn’t won a Big Ten game since 2023.
MLive staff picks:
- Purdue +20.5: McMann, Richman
- Michigan -20.5: Kahn, Wenzel, Zuke
